While small bone defects heal spontaneously, large bone defects need surgical intervention for bone transplantation. Autologous\r\nbone grafts are the best and safest strategy for bone repair. An alternative method is to use allogenic bone graft. Both methods\r\nhave limitations, particularly when bone defects are of a critical size. In these cases, bone constructs created by tissue engineering\r\ntechnologies are of utmost importance. Cells are one main component in the manufacture of bone construct. A few cell types,\r\nincluding embryonic stem cells (ESCs), adult osteoblast, and adult stem cells, can be used for this purpose. Mesenchymal stem\r\ncells (MSCs), as adult stem cells, possess characteristics that make them good candidate for bone repair. This paper discusses\r\ndifferent aspects of MSCs that render them an appropriate cell type for clinical use to promote bone regeneration.
Loading....